官网链接
折扣/货期| 货号：38579-1 mg | 规格：1 mg | 目录价：￥364 |
| 货号：38579-10 mg | 规格：10 mg | 目录价：￥1820 |
| 货号：38579-25 mg | 规格：25 mg | 目录价：￥4102 |
| 货号：38579 | 规格：5 mg | 目录价：￥1190 |
产品详情
产品名称:
Trofinetide (acetate)
别名:
NNZ-2566
产品描述:
Trofinetide is a derivative of the neuroprotective tripeptide Gly-Pro-Glu, an N-terminal sequence found in insulin-like growth factor-1 (IGF-1).{67453} It decreases cell death induced by the protein phosphatase inhibitor okadaic acid (Item No. 10011490) in primary rat embryonic striatal neurons when used at a concentration of 10 nM. Trofinetide reduces brain expression of mRNA encoding IL-1β, TNF-α, IL-6, and E-selectin in a rat model of neuroinflammation induced by a penetrating ballistic-like brain injury.{67454} It reduces cortical and striatal infarct area in a rat model of brain injury induced by middle cerebral artery occlusion (MCAO) when administered at doses of 30 and 60 mg/kg.{67453} Trofinetide (100 mg/kg per day) reduces the number of dendritic spines and reverses deficits in social recognition and contextual fear conditioning, as well as decreases testicular weight gain, in an fmr1-/- knockout mouse model of fragile X syndrome.{67455} Formulations containing trofinetide have been used in the treatment of Rett syndrome.
保存温度:
-20
运输温度:
-20
预期分子量:
315.3
产品形式:
A solid
有效期:
1460
纯度:
≥95%
分子式:
C13H21N3O6 • XC2H4O2
您可能感兴趣的产品
Caspase 13 Peptide
货号：GTX85523-PEP
SKI Peptide
货号：GTX85522-PEP
PERP Peptide
货号：GTX85520-PEP
West Nile virus Capsid peptide
货号：GTX85510-PEP
West Nile virus Capsid peptide
货号：GTX85509-PEP
West Nile virus Envelope Peptide
货号：GTX85506-PEP
CTRP4 Peptide
货号：GTX85503-PEP
Precerebellin Peptide
货号：GTX85499-PEP
促销活动
相关产品推荐
Cotadutide (acetate)
货号：40714
Fexapotide (trifluoroacetate)
货号：40716
Myristoyl Hexapeptide-16 (hydrochloride)
货号：40513
[Gly8,36,Glu22]-GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (acetate)
货号：40298
[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)
货号：40149
Myomodulin A (Aplysia, Lymnaea) (trifluoroacetate salt)
货号：40151
