货号:AG-40B-0239-C050 | 规格:50 ug | 目录价:¥4800 |
产品详情
产品名称:
VSTM5 (mouse):Fc (mouse) (rec.) (non-lytic)
别名:
V-set and Transmembrane Domain-containing Protein 5
产品描述:
The V-set and transmembrane domain-containing protein (VSTM) family is composed of 8 proteins: VSTM1v1, VSTM1v2, VSTM2a, VSTM2b, VSTM2L, VSTM3, VSTM4 and VSTM 5. Members of the VSTM family are associated with the regulation of functions of immune cells, adipose cells and neuronal cells. The VSTM family is an immunoglobulin (Ig) superfamily that shares structural similarities with the B7-like transmembrane proteins involved in immune regulation. VSTM1 and VSTM4 play positive and negative roles in macrophage activation, respectively. VSTM3 (TIGIT) acts as a co-inhibitory receptor that suppresses the cytokine production of T cells and NK cells. V-set and transmembrane domain-containing protein 5 (Vstm5), a newly characterized small membrane glycoprotein highly expressed in the CNS, facilitates the formation of neuronal dendrites and protrusions such as dendritic filopodia. Regulatory roles of VSTM5 for in vitro and in vivo immune responses have been reported. VSTM5 functions as a novel immune checkpoint by regulating T cell proliferation and cytokine production, Treg generation by maintenance of T cell energy and possibly induction of T cell apoptosis.
宿主来源:
CHO cells
产品浓度:
1mg/ml after reconstitution.
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~60kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C.Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test).
您可能感兴趣的产品
Human UFC1 protein, His tag
货号:GTX68512-pro
Human DcR2 / CD264 protein, human IgG1 Fc and His tag (active)
货号:GTX66967-pro
Mouse CTLA4 protein, mutant mouse IgG2a Fc tag (active)
货号:GTX65784-pro
Mouse TIM-4 protein, human IgG1 Fc tag (active)
货号:GTX65783-pro
Mouse TIM-1 protein, mouse IgG2a Fc tag
货号:GTX65774-pro
Mouse CD86 protein, mouse IgG2a Fc tag
货号:GTX65769-pro
Mouse CD80 protein, mouse IgG2a Fc tag
货号:GTX65767-pro
Mouse CD74 protein, mouse IgG2a Fc tag
货号:GTX65766-pro
促销活动
精品推荐
相关产品推荐
CD134 [OX40] (mouse):Fc (human) (rec.)
货号:CHI-MF-111CD134-C100
CD279 [PD-1] (mouse):Fc (human) (rec.)
货号:CHI-MF-111PD1-C100
Semaphorin-4A (mouse):Fc (human) (rec.)
货号:CHI-MF-111SEMA4-C100
Tim-1 (mouse):Fc (human) (rec.)
货号:CHI-MF-111T1-C100
Tim-2 (mouse):Fc (human) (rec.)
货号:CHI-MF-111T2-C100
Tim-4 (mouse):Fc (human) (rec.)
货号:CHI-MF-111T4-C100