CCL20 (human):Fc (human) (rec.)-Fc融合蛋白-ELISA_抗体_蛋白_核苷酸

首页产品中心 Fc融合蛋白

CCL20 (human):Fc (human) (rec.)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-HF-210CCL20-C050

规格：50 ug

目录价：￥4340

产品详情

产品名称:

CCL20 (human):Fc (human) (rec.)

别名:

Chemokine (C-C motif) ligand 20; LARC; MIP-3A; ST38; Scya20; Exodus-1

产品描述:

Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products. MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Deregulation of miRNAs and chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis and the regulation of CCL20 expression by miR-21 might be a regulatory mechanism involved in progression of colorectal cancer (CRC).

宿主来源:

HEK 293 cells

保存温度:

-20°C

运输温度:

BLUE ICE

预期分子量:

~38kDa (SDS-PAGE, reducing conditions)

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.