货号:CHI-HF-210CD38-C100 | 规格:100 ug | 目录价:¥5040 |
产品详情
产品名称:
CD38 (human):Fc (human) (rec.)
别名:
ADP-ribosyl Cyclase 1; Cyclic ADP-ribose Hydrolase 1; ADPRC 1; T10
产品描述:
CD38, also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.
宿主来源:
HEK 293 cells
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~70kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
内毒素水平:
<5EU/mg protein (LAL test; Lonza).
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