货号:AG-40A-0077Y-C010 | 规格:10 ug | 目录价:¥2880 |
货号:AG-40A-0077Y-C050 | 规格:50 ug | 目录价:¥5280 |
产品详情
产品名称:
DLL4 (human):Fc (human) (rec.)
别名:
Delta-like Protein 4; Delta4
产品描述:
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
宿主来源:
HEK 293 cells
靶标/特异性:
Interacts with human Notch1 (as confirmed by flow cytometry).
产品浓度:
After reconstitution:for 10µg size: 0.1mg/mlfor 50µg size: 1 mg/ml.
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~100kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS + 0.5 % Trehalose.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Inhibits adipogenesis of 3T3L-1 cells and mesenchymal stem cells (MSCs). Induces the Notch target gene HES-1 when coated on a plate at 1µg/ml.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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